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Regarding IGF system gene expression, Igf1r mRNA expression increased significantly in Igf1r fl/fl mice upon experimental pulmonary metastasis, showing an efficient depletion in PBS- and LLC-challenged CreERT2 mice, as expected due to tamoxifen-mediated Igr1r gene depletion

En exmenes auxiliares: hemoglobina en 10,2 mg/dl, VCM 77, resto no significativo

Liraglutide (Victoza, Saxenda) Approved for obesity at higher doses, typically results in 57% weight loss

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