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We demonstrate mechanistically the need for increased mitochondrial function, facilitated by mTORPGC1-mediated mitochondrial biogenesis, to support rebalancing of pyrimidines via UCK2 to support cellular survival in the face of continued 5FU treatment
As a proof of concept, we herein propose to use dimeric copper peptide (D-CuP) for diabetic wound treatment
These findings suggest that GLP-1 receptor agonists may offer a critical advantage in managing diabetes and cardiovascular risk in patients with inflammatory arthritis, said Antonio Avia-Zubieta, Senior Scientist at Arthritis Research Canada and Principal Investigator in this study
Type 2 Diabetes Mellitus (T2DM) is one of the most common metabolic disorders worldwide
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