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Studies have shown that trehalose can modulate glucose metabolism and insulin sensitivity in healthy subjects [3032]
The calcium-dependent binding of CAO to ANT induces a conformational change (Halestrap et al., 2002) which results in the opening of the mitochondrial permeability transition pore (MPTP) and allows the equilibration of small solutes and the release of pro-apoptotic proteins from the intermembrane space
Genet Metab
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