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it reflects the reward-pathway mechanism at work

This matters as a new cornerstone therapy in type 2 diabetes (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1), are entering broader use, necessitating a deeper dive into how this treatment interacts, directly or indirectly, with pathways influenced by sex hormones

7,8 By modulating complex cellular and molecular pathways, biologics have the potential to address these unmet needs, thereby shifting cardiovascular treatment from symptom control to disease modification

This positive effect on UPS activity helps combat the accumulation of damaged proteins, a hallmark of aging