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It is worth noting that fatigue may appear before anaemia develops in some cases, as the neurological and metabolic effects of B12 deficiency can manifest independently of haematological changes

[2] When to Seek Further Medical Advice About B12 Patients should maintain regular contact with their GP or healthcare team throughout B12 treatment, but certain situations warrant urgent medical review

Many researchers find their optimal response at 5-10mg weekly

The combination of Vitamin B12 injections, along with exercise and a balanced diet, can help substantially in a persons efforts at losing weight or maintaining physical fitness