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The first inhibitors were characterized in the late 1980s and 1990s
Fixed tissues were incubated in 10% sucrose in 1 PBS for 30 min and then incubated in 20% sucrose in 1 PBS at 4 C for 4 h, followed by embedding in OCT mounting compound (TissueTek, Sakura) on dry ice and stored at 80 C
Professor Atherton has received travel sponsorship and/or honoraria or consultancy payments (made to his employer) from or undertaken clinical trials sponsored by Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly and Novo Nordisk
Combined with peptide anti-inflammatory effects creates comprehensive approach
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