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patients overcame many barriers by paying cash 53% of filled GLP-1 scripts were cash-paid in 2024 (up from 11% in 2023) ( [11] )
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The goal is weight loss AND improved health not weight loss at the expense of neurological symptoms
These studies will provide important insights into the how GLP-1R activation in the VTA alters dopamine signaling to influence activity in the two main output pathways of the striatal complex and ultimately decrease cocaine seeking
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