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Researchers have discovered that the GABA system is inhibited in the pathogenesis of depression (51, 163, 164), resulting in less secretion of GABA in the brain
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Therefore, the differences in these proteins could explain the reduced expression of GshF in the mutant ZJ12345 compared to the wild type strain and help explain why the mutant required a higher IPTG concentration to obtain GshF activity similar to the wild type host strain
Ill also explain how it is absorbed and how it interacts with genetic variants, such as COMT
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