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Side Effect Mitigation The primary motivation for microdosing is reducing adverse effects: Theoretical advantages: Lower peak concentrations reduce nausea intensity Gradual exposure allows GI adaptation Reduced gastroparesis severity Better maintenance of normal eating patterns 2
E., Lakha, S
2007;110(2 Pt 2):480-482
According to our in silico predictions, the changes in metabolic fluxes in the mutant significantly impacted arginine synthesis and pathways related to NAD metabolism, indicating a redistribution toward stress protection in response to decreased glutathione content
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