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Neuroimaging studies have found that patients with hyperthyroidism had reduced grey matter volume in portions of the occipital lobe (lateral occipital sulcus and fusiform gyrus) in the left hemisphere, the frontal and parietal lobes (insula, paracentral, precuneus, superior frontal cingulate, superior parietal and postcentral) in the right hemisphere
This method is particularly useful for peptides that target cognitive or neurological functions, as the nasal cavity provides a pathway that is close to the central nervous system
A larger two-centre study in 2024 showed no increased risk of aspiration with GLP-1RA compared with sodium-glucose cotransporter-2 inhibitors, but there were higher rates of abandoned procedures in the GLP-1RA group (OR 1.99, 95% CI 1.56 to 2.53).31 A prospective observational study in volunteers taking semaglutide and controls performed gastric ultrasound after an 8 hour fast
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