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Understanding the mechanisms behind these medications reveals that, while they promote beneficial changes in appetite and metabolic health, they can also lead to feelings of tiredness due to factors such as altered digestion, fluctuations in blood sugar, and hydration levels

Small human studies and observational analyses have also suggested reductions in substance cravings, relapse rates, and alcohol-related hospitalizations among some patients receiving GLP-1 therapies

That is 4.5 percentage points higher than Phase 2 (24.2% at 48 weeks, Jastreboff et al

Any use outside this age range would need to be specifically determined by a licensed clinician on a case-by-case basis