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Reduction in Appetite and Caloric Intake: By affecting hunger hormones and gastric emptying, GLP-1 can help reduce appetite and caloric intake, leading to weight loss

Retatrutide, a triple agonist in Phase 3 clinical trials, produced average weight loss of 24 percent at 48 weeks in Phase 2 data (Jastreboff et al., NEJM , 2023)

Semaglutide: Also given as a weekly subcutaneous injection, semaglutides dosage increases monthly as tolerated until a maintenance dose is reached

TB4 and, by extension, TB-500 may work on a cellular level to reduce inflammation by regulating autophagya process of cellular waste disposal [28]