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Occasional nausea has been reported, especially when taking the compound without food
TB-500 partially replicates this function on fragment 17-23, considered the minimal active sequence
40 Four RCTs have evaluated the effects of B12 in depression
These diverge, and they diverge in a predictable direction: a preparation that has partially dissociated or partially denatured usually keeps most of its antibody-binding surfaces intact while losing activity, so the immunoassay reads close to expectation while the biological readout has fallen
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