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High IL-6 plasma levels were shown to have a greater likelihood of mortality, morbidity, and disability in the elderly (Puzianowska-Kuznicka et al., 2016)
P2X 3 -mediates ATP signalling from L-cells to nodose neurons Consistent with the concept of purinergic signalling between L-cells and the afferent vagus nerve, qPCR analysis of fresh and cultured ND ganglion neurones identified expression of P2rx2 and P2rx3 subunits (Fig
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