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No published receptor binding constant or characterised minimum effective concentration anchors the dose, so dose decisions rest on preclinical envelopes. TB-4: cell migration What it is TB-4 is a naturally occurring 43-amino-acid peptide involved in cell movement and tissue repair

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In response to oxidants, cysteine modification on Keap1 releases NE2FL2, which is then stabilized and transported to the nucleus where it activates transcription of antioxidant genes, including proteasomal PA28

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