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This is especially important, as the mitochondria is a major site of free radical generation and oxidative stress.3, 4, 7 In conclusion, melatonin obviously has a variety of beneficial effects with reference to cardiovascular pathophysiology, including hypertension, diabetes mellitus, dyslipidemia, and I/R injury

Non-alcoholic beverages: Green tea is a good substitute for caffeine and alcohol, containing plenty of flavonoids to prevent oxidative cell damage that could worsen OA