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Co-immunoprecipitation analysis revealed that BPC 157 reduced the inhibitory binding between Cav-1 and eNOS, thereby activating eNOS

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In the unilateral ureteral obstruction model, liraglutide suppressed TGF- expression and downstream Smad3 and ERK1/2 signalling, resulting in reduced tubulointerstitial collagen accumulation and improved histological fibrosis scores [56]