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Doctors can usually prescribe different medications within the same class, like GLP-1 receptor agonists, based on clinical judgment, although [this] varies due to factors like insurance requirements, formulary restrictions, medical history, and treatment goals, said Yoshua Quinones, MD, an internist with Medical Offices of Manhattan and contributor to LabFinder

What to supplement: Increase dietary protein first (see foods section below) Consider methionine supplements (500-1000mg daily) under practitioner guidance May benefit from small amounts of methylated B vitamins once protein intake is adequate If you have B-vitamin deficiencies: Paradoxically, severe B12 or folate deficiency can cause low homocysteine because you cant recycle it properly

GLP-1 medications can indirectly affect several of these factors by reducing appetite and overall calorie consumption