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In addition to being a therapeutic target, oxidative stress has been shown to decrease the GSH:GSSG ratio which has proven useful as a clinically accessible, pharmacodynamic biomarker of immune redox tone for conditions such as malignancy (Zitka et al., 2012)

Furthermore, the over-expression of DHAR which led to reduced lipid peroxidation in the transgenic plants led to delayed leaf aging in O

AMPK activation causes cells to utilize their stored fuel more efficiently, improving insulin sensitivity and glucose uptake into muscles