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Lyophilized peptides are typically stable at room temperature for several weeks or longer, so if they will be used within weeks or months, this type of storage is usually adequate
A study conducted at the University of Texas Southwestern Medical Center found that NNMT inhibition in obese mice reduced body weight by 7% over four weeks without changes in food intakea reduction driven entirely by increased energy expenditure
However, evidence from research studies suggests that GLP-1 analogs may also reduce gastric acid secretion, which can impair the conversion of dietary B12 into its absorbable form and decrease binding to intrinsic factor, both of which are necessary for proper absorption
Preclinical studies in diet-induced obese mice have examined its effects on adipose tissue and glucose tolerance
