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In addition to the cohort studies, four meta-analyses confirmed a higher frequency of vitamin B12 deficiency in patients with T2D taking metformin [28-31]
Additional Glacial Acetic Acid and/or Sodium Acetate may have been used to adjust pH
Methionine is an amino acid that acts as a lipotropic agent
They may need to rely on supplements or vitamin B12 injections to maintain adequate levels, and the frequency of supplementation will affect how long the vitamin stays in the body
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