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While it seems like they are brand new, GLP 1s have been studied since the 1980s and have been available to the public for the treatment of diabetes since 2005
Soon, weight loss and improved cardiovascular health were noted in patients taking the breakthrough medication for diabetes, sparking approval of related drugs for obesity
Its physiological actions include: Increasing glucose-dependent insulin secretion Suppressing glucagon release Delaying gastric emptying Reducing appetite and caloric intake Enhancing satiety Improving insulin sensitivity Promoting weight reduction The major limitation of native GLP-1 is its ultra-short half-life due to rapid degradation by DPP-4 enzymes
"Kenyan school children have multiple micronutrient deficiencies, but increased plasma vitamin B-12 is the only detectable micronutrient response to meat or milk supplementation"
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