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The timeline varies by injury severity, with acute injuries responding faster than chronic conditions that have been present for months or years

For others, absorption may be limited due to digestive concerns, medications, or individual differences

Occasional reports include temporary fatigue or lethargy (5-10% of users), mild headaches in the first few days of use, slight water retention, or transient flushing at injection sites

At our clinic, patients who come in with chronic GI inflammation, SIBO residuals, or a history of NSAID-induced gastritis are the group most likely to report subjective improvement on BPC-157 within the first 30 days