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The synergy between the two pathways is what makes the combination dosing more efficient per unit of compound
Hepatocytes were lysed in lysis buffer containing protease cocktails inhibitor (Beyotime, P1005) and PMSF (Phenylmethanesulfonyl fluoride, Beyotime, ST506), as well as centrifuged at 12000 r/min, 4 C, for 15 min
Another potential limitation of the study according to the AAOph and the North American Neuro-Ophthalmology Society was that all patients included were seen at Massachusetts Eye and Ear in Boston
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