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10.1016/j.isci.2023.106057 Summary Keywords drug mechanism, metformin, type 2 diabetes, gastrointestinal tract, gut microbiota Citation Cheng M, Ren L, Jia X, Wang J and Cong B (2024) Understanding the action mechanisms of metformin in the gastrointestinal tract

Further studies with larger sample sizes and longer follow-up periods are needed

The FLOW trial with semaglutide showed significant reductions in kidney disease progression and cardiovascular death in patients with type 2 diabetes and chronic kidney disease

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