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Nrf2 is involved in not only the regulation of GSH synthesis and reduction via upgrading some enzymes and proteins (SLC7A11, GCLM, GCLC, GR) but also the activation of GSH-dependent antioxidant enzymes (GPX, GST) [200, 201]

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In the article, the many functions of glutathione are described as follows: Clinically, glutathione is thought to critical for the following disease and body processes References Mechanism of Action 1-4 Glutathione has many mechanisms in the body to support its role as an antioxidant, a detoxifier, and its involvement in many enzymatic processes including redox reactions

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