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Another study investigated whether the zinc complex of L-carnosine, polaprezinc (3 mg/kg, p.o), inhibited paclitaxel-induced mechanical allodynia and migration of macrophages in dorsal root ganglion cells without affecting the antitumor activity exerted by paclitaxel in cell lines and tumor-bearing mice [145] (Fig

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Because GLP-1 receptors exist in the central nervous system, medications like semaglutide can influence more than just hunger

Although participants on semaglutide 2.4 mg had a significant reduction in SBP and DBP compared with placebo, in our ITT analysis, the adjusted mean difference in SBP fell short of statistical significance ( P = 0.059)