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found that active GSH metabolism within tumors further suppresses immune responses, such as IFN- signaling and PD-1/PD-L1 interactions, while reducing the number of M1 macrophages and increasing the proportion of M2 macrophages
Notably, the present narrative review is an extension of a previous review article that covered polyphenols and/or phytoestrogens that included daidzein, equol, genistein, and resveratrol as supplemental therapies for skin aging, which was published in Dermatology and Therapy earlier this year by Lephart (2025) [9]
An important role of folic acid is the formation of methionine from homocysteine using vitamin B12 as a cofactor
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