Turton MD, OShea D, Gunn I, Beak SA, Edwards CM, Meeran K, Choi SJ, Taylor GM, Heath MM, Lambert PD, et al
While lipophilicity, dipole moment, and size are factors that influence the ability of a compound to enter the hydrophobic core of a cell membrane, the lipid bilayer environment is too chemically complex, fluid, and heterogeneous for these indicators alone to provide accurate estimates of transport kinetics
T.et al (2024)
An experimental GLP-1 pill helped people with obesity lose a significant amount of weight in a late-stage clinical trial, which suggests people who fear needles might soon have a way to take these medicines without the need for injections