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Model , 2023 , 64 , 1, 917

Interestingly, a ferroptosis inhibitor, FER1, could partially restore reduced cell viability afforded by FXR1 depletion, suggesting the possible involvement of FXR1 in the regulation of ferroptosis (Figures 5A, B)

Front Nutr 8:642628

These simulations utilized the lowest-energy solution of the NMR-derived ensemble of the p53 TAD2 -FOXO4-DRI complexes as our starting geometry (see methods)