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In Tg2576 mice, which overexpress the amyloid precursor protein (APP) with the Swedish mutations (K670N and M671L), researchers observed increased brain uptake of albumin and fluorescein, as well as increased extravasation of immunoglobulin G (IgG) and fibrin, indicating compromised BBB integrity [67,68,69]
Glucagon like peptide-1 (736) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus
Each group was randomized by using the website www.randomization.com
PMC 6361125
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