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In animal models, findings suggest stronger responses in obese specimens compared to lean ones

Acute perioperative- stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition

Metoclopramide and erythromycin are the two most commonly used agents used to manage gastroparesis and there is potential that the GLP-1 agonists will oppose the prokinetic effects of these agents Corticosteroids Corticosteroids are notorious for raising blood sugars which could directly oppose the blood sugar lowering effects of GLP-1 agonists