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Eligible subjects were healthy male or female Chinese subjects, aged 1855 years, with a BMI of 20.024.9 kg/m 2 and a body weight 54.0 kg
GLP-1 Receptor Agonists, Obesity, and Cardiovascular Disease Glucagon-like peptide-1 receptor agonists (GLP-1RAs) were originally developed to improve glycemic control in type 2 diabetes but have since demonstrated benefits in weight reduction and cardiovascular risk modification, including in people without diabetes
Heading the list were the long-awaited results of TECOS, which looked at the cardiovascular (CV) safety of Merck & Co's DPP-4 inhibitor Januvia (sitagliptin) and concluded that there was no elevated risk with the drug in patients with established CV disease
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