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Disadvantages More discomfort: Deeper injection into muscle tissue with larger needles produces more sensation
Black Box Warning Although rare, dulaglutide caused thyroid C-cell tumors in animal studies
Updated July 2026 GLP-1 medications started as diabetes drugs and became famous for weight loss
In a number of studies, GLP-1R agonists such as liraglutide, exenatide and lixisenatide can reduce neuroinflammation in AD models, thereby improving cognitive dysfunction (140, 141, 144148)
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