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Special Populations: Dosage may be adjusted for individuals with specific medical conditions, such as severe deficiencies, and should be determined by a healthcare professional

Direct human oral dose-finding trials are limited

This GHR upregulation sensitises local cells to circulating GH, potentiating GH-induced JAK2/STAT signalling and stimulating collagen matrix synthesis, IGF-1 production, and fibroblast proliferation providing a mechanism through which BPC-157 engages the GH/IGF-1 axis at the tissue level without altering systemic GH secretion

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