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High-dose B6 can interfere with anemia medications, IV magnesium can cause dangerous blood pressure drops, and high-dose vitamin C can affect blood clotting tests

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Antioxid Redox Signal 30:12381268 Winkler BS, Orselli SM, Rex TS (1994) The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective

Developmental or acute elevations of KYNA impair adult cognitive function and spatial learning, whereas reductions in KYNA improve cognitive performance [73,74,75]