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The tesamorelin group showed significantly better performance on tests of executive function and verbal memory compared to placebo an effect attributed to IGF-1's neuroprotective role
However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program
This is particularly relevant for those living in high-pollution urban areas, where airborne toxins can settle on the scalp and trigger inflammatory reactions
Low androgens, namely testosterone, and decreased androgen receptors have been linked with sexual dysfunction and increased risk of cardiovascular disease and metabolic syndrome occurrence
