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for instance, case reports have demonstrated survival after a 25 g overdose [42] , and current guidelines in the United States and Canada indicate a high-risk ingestion to be ingestion of at least 30 g of APAP [43]
It should be noted that GSH data obtained from post-mortem brain samples are variable in quality, as brain GSH is affected by many pre- and post-mortem factors and changes quickly after death [19, 20]
These processes include chromosomal maintenance, oxidative balance, and neuroendocrine signaling pathways
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