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Heavier individuals may require higher doses to achieve equivalent NNMT inhibition due to larger adipose tissue mass and potentially higher baseline NNMT activity
In contrast, animals treated with 200 M neomycin for thirty minutes exhibit dim or completely absent fluorescence
The multi-use capability supports protocol continuity across repeated laboratory sessions
Both have overlapping roles, but overexpression studies made clear that KRPs inhibit both M- and S phase entries, while SMRs are assumed to merely negatively affect mitosis (Kumar and Larkin 2017)
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