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The main metabolite, [ 3 H]proline (M1), accounted for 4.96% (female) and 3.93% (male) of the bile samples (Figure 5C)

Established therapeutic approaches have demonstrated efficacy through rigorous clinical trials and should remain the foundation of autoimmune disease management

12 The substitution of GLP-1 Thr 13 or GIP Ile 7 with Ala obviously decreased their receptor-activating activities 25,26 and the substitution of GIP Ile 7 with Thr decreased its cAMP activity (pEC 50 : 9.769.58;Emax: 9.918.90)