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Not just a few exceptional responders pulling up the average, but broad, reliable weight loss across the study population
Genetics, blood pressure, cholesterol, diabetes, smoking, kidney function, age, and lifestyle remain major determinants of cardiovascular risk
This study enrolled adults with obesity (body mass index 30 kg/m) without type 2 diabetes, and a separate cohort with type 2 diabetes, across multiple international sites
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, whereas semaglutide only targets the GLP-1 receptors
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