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(91), in a 16-week randomized, double-blind, cross-over study with 27 adolescents suffering from migraines, suggested that dietary supplementation with fish oil rich in very long-chain omega-3 PUFAs could reduce the frequency, duration, and severity of migraines, a benefit also observed with olive oil

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The primer sequences and TaqMan assay IDs are listed in Additional file 1

It should be noted that GCLM KO mice have systemic GSH deficiencies, ranging from 10 to 40% of normal levels depending on the tissue type 16