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Rural areas, in particular, often experience longer delays due to the additional challenges of transporting and storing temperature-sensitive medications

Reports of adverse effects following acute or acute-on-chronic exposures remain incompletely characterized, and existing literature has not clarified whether new toxicity patterns emerge when these drugs are used primarily for obesity rather than diabetes. For this analysis, researchers tracked years of data from the National Poison Data System, identifying more than 3,000 incidents prior to that 2021 approval and nearly 7,000 incidents after it

doi:10.1002/14651858.CD014885.pub2 141

The normal situation for a person would be to release sugar into the circulation unless you don't need it