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The AHCY gene encodes adenosylhomocysteinase
Rather than being limited to one specific area of research, it has become associated with studies spanning tissue biology, cellular communication, vascular biology and extracellular matrix research
10.1016/s0958-1669(00)00199-3 55 UribeP
In streptozotocin-induced diabetic rats, there was decreased transketolase expression and activity in renal glomeruli, liver, skeletal muscle and RBCs after 12 weeks of diabetes was found associated with progressive increase in the renal clearance of thiamine and increased albuminuria with duration of diabetes, suggesting that abnormal renal handling of thiamine may occur early in the process of impairment of renal function in diabetes [190]
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