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The first two bind to the xenobiotic response element (XRE) sequences, while the last binds to the NF-B binding site in the NFE2L2 promoter, inducing its transcription [171,172,173,174], with a consequent increase of NFE2L2 mRNA available within the cell
A photoreactive analog of IngMeb together with quantitative proteomic experiments were used to discover targets of IngMeb in human cancer cell lines and primary human keratinocytes
Egan, M
Injection site reactions including localised itching, redness, and swelling are common (up to 1 in 10 patients) and typically mild and self-limiting
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