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The four primary mechanisms are: signaling the hypothalamus to suppress hunger, slowing gastric emptying so fullness lasts longer, stimulating insulin release after meals to prevent blood sugar spikes, and suppressing glucagon to reduce glucose release from the liver

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140 However, another small clinical study found that people with celiac disease who took AN-PEP and introduced gluten under controlled conditions did not exhibit significantly different celiac disease quality scores or gut lining health upon close examination (histology) compared with those who took a placebo

Evidence-based approach to fiber supplements and clinically meaningful health benefits