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These changes will also assist with long-term success, as they will help you maintain the weight loss once you stop taking the medication
For example, multiple acyl-CoA dehydrogenase deficiency (MADD), caused by mutations in genes that impair the activity of enzymes involved in the transfer of electrons from acyl-CoA to coenzyme Q 10 , is usually responsive to riboflavin monotherapy yet patients with low coenzyme Q 10 concentrations might also benefit from co-supplementation with coenzyme Q 10 and riboflavin (27)
For genes with zero counts in all samples (very few), a count of 1 was added to the sample with the largest library size to enable model fitting
