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Nevertheless, despite demonstrating potent in vivo effects, neither study performed side-by-side dose-response benchmarking against clinical ACE inhibitors (e.g., lisinopril or captopril) under identical assay conditions

Our study also featured predominantly male children

Thanks to the presence of GR, a single molecule of GSSG is reduced to two molecules of GSH, so that the presented method measures total GSH as the sum of reduced and oxidized GSH ([GSH] total = [GSH] + 2 x [GSSG]) (Rahman et al., 2007)