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The conditions that have been associated with glutathione deficiency include the following: Neurodegenerative diseases such as Alzheimers, Parkinsons and Huntingtons disease and ALS Pulmonary diseases such as COPD, asthma, and acute respiratory distress syndrome Immune system disorders Cardiovascular diseases such as high blood pressure, elevated cholesterol, and heart attacks Chronic age-related disorders such as cataracts, macular degeneration, hearing impairment, and glaucoma Liver disease Cystic fibrosis Aging processes (Pizzorno, 2014)

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[8] Medium spiny cells are a typical example of inhibitory central nervous system GABAergic cells