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How Defendants Challenge Causation Defendants often argue that gallbladder disease or other complications occurred independent of medication use

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bFGF protects against oxygen glucose deprivation/Reoxygenation-induced endothelial monolayer permeability via S1PR1-dependent mechanisms

When children remain refractory to acute or prophylactic treatment, or the episode differs from previous ones, the clinician should consider the possibility of an underlying disease and further mono- or combination therapy and psychotherapy can be guided by accompanying comorbidities and specific sub-phenotype